
A | Trump-era adviser John Bolton responded to surging backlash against him on Wednesday, remarking that individuals who opposed his recent remarks on US-staged coups were nothing more than “snowflakes.”,Bolton’s comments came a day after he casually admitted to having taken part in planning a coup d’etat during an on-air discussion with CNN’s Jake Tapper on Tuesday. At the time, the pair had been weighing in on the latest revelations from the Capitol riot public hearings.,However, firing back at his critics on Wednesday, Bolton stated during an interview with conservative news outlet Newsmax that those in opposition to his beliefs simply are not grasping what is needed to “protect” the Land of the Brave.,“I think there are a lot of snowflakes out there that don’t understand what you need to do to protect the United States,” Bolton said.,While Bolton did not specify during the CNN interview which country’s government he tried to overthrow, he did mention that he wrote about Venezuela in his memoirs. “Not that we had much to do with it,” Bolton quickly backtracked at the time, “but I saw what it takes for an opposition to overthrow an illegally elected president, and they failed.”,During the Newsmax interview, Bolton continued, implying that coups are what presidents need to do to keep Americans safe.,“I'm not going to get into specifics. I did write about Venezuela in my memoir, and I think that any president that's not willing to do what it takes to protect the interests of the American people needs to have some counseling.”,Newsmax anchor Bianca de la Garza did not ask a follow-up question.,During the Trump administration, the United States backed opposition candidate Juan Guaidó as the legitimate president of Venezuela.,An attempted coup d’état, known as Operation Gideon, saw members of a private military group, Silvercorp USA, attempt to remove Venezuelan President Nicolás Maduro from power and arrest him; however, the attempt was quickly snuffed out by the Venezuelan government. Multiple Venezuelan opposition fighters were killed and two former US Special Forces members were arrested by the Venezuelan government.,Officially, the State Department denied any involvement in the coup.,Even though Maduro controls most of the power levers in the country, the State Department continues to recognize Guaidó as the interim president of Venezuela.,Video: Juan Guaido Chased Out of Venezuelan Restaurant as Chairs Go Flying Once Again12 June, 04:23 GMT,But relations have thawed somewhat as of late, with the Biden administration seeking relief from record high oil prices in the United States. In May, the United States dropped some sanctions on Venezuela and allowed Chevron to start negotiations with the Maduro government, something it previously forbade. Still, the Biden administration has continued the policy of officially recognizing Guaidó as the legitimate interim president of Venezuela, despite the fact that many Venezuelans have rejected Guaidó as the country’s leader.,Beyond failing to enact regime change in Venezuela, Bolton was also a strong proponent of invading Iraq and has advocated using military force against Iran on multiple occasions. He also worked at the State Department between 2001 and 2005, when there was a failed coup attempt against former Venezuelan President Hugo Chávez in 2002 that was linked to Bush administration officials.。

B | 美国当地时间9月12日,美国总统拜登签署了一项行政命令,以启动一项国家生物技术(Biotechnology)和生物制造(Biomanufacturing)倡议,涉及提高美国国内生物制造能力、扩大生物产品的市场机会等多个方面。此举旨在推动美国生物制造的进步。CXO是指药品从研发、临床试验、生产到上市过程中的一系列外包活动,产业链上下游包括CRO、CDMO/CMO、CSO,分别服务于医疗行业的研发外包、生产外包、销售外包三个环节。2021年以来,国内CXO行业迎来高速发展期,持续拓展海外市场。图片来源:图虫网9月13日,时代周报记者致电多家CXO企业。凯莱英方面表示,“公司在美国主要为小分子化药方面的合作,没有生物制药方面的业务。

C | ”博腾股份方面亦表示,在美国的业务以小分子为主,该项政策刚宣布,还没有具体举措,对公司业务尚未有实质性影响。

D | 泰格医药回应称,从目前公开消息来看,主要针对的是临床前CRO业务,对泰格医药目前业务没有影响,公司不涉及CDMO和生物医药业务。CIC灼识咨询合伙人王文华向时代周报记者解释,美国旨在鼓励本土生物制药产业发展,在细则出台之前对国内CXO企业的业绩影响尚不明朗。判断CXO行业发展趋势更侧重于基本面,此次政策影响偏向短期,对长期市场成长影响不大。

E | 王文华解释,国内CXO企业在生物制药的外包服务方面的优势得天独厚。其一,国内CXO企业的人力成本较低,且有充足的化学、药学等科研人员储备;其二,中国是全球最大的原料药生产国;其三,中国庞大的人口基数与充足的患者病例资源,国内CXO在临床阶段可针对各类细分疾病做到快速大量入组,加快新药研发进度。王文华还指出,国内CXO企业是国外生物制药企业的理想合作对象。近年,国内CXO企业在手订单飞速增长、海外市场份额持续提升。“国内CXO企业长期会经历持续稳定的市场空间拓展。” 王文华说。去年以来,国内CXO行业业绩增长强劲。2022年上半年,主要CXO公司的营收、净利均呈现稳定增长趋势。与此同时,多家CXO主要收入也多来自国外市场。

F | 西南证券研报数据显示,在CXO板块的16家代表性企业中,2022年上半年合计收入426亿元,上涨73.2%;归母净利润约118.4亿元,涨86.6%;扣非归母净利润约95.9亿元,涨104.5%。

G | 药明康德是CXO板块龙头,目前市值2260.22亿元。药明康德通过全球32个营运基地和分支机构,为来自全球超5850家客户提供服务。2022年年中报显示,报告期内,药明康德实现营收177.56亿元,同比上涨68.52%;扣非净利润38.5亿元,同比上涨81%。其中,药明康德来自美国客户收入为119.09亿元人民币,同比增长104%,占总营收67.07%。9月13日上午,药明康德方面回应称,目前,公司业务和运营一切正常。2022年上半年,康龙化成营业收入46.35亿元,同比上涨41.06%。随着国际化战略的推进,公司在英国和美国共有11个运营实体,超过1300名员工。2022年上半年,海外子公司营业收入占公司营业收入的12.14%。同期,博腾股份营收39.14亿元,同比上涨211.67%。2022年中报显示,公司于2017年收购的J-STAR,已在美国拥有2个研发厂地,能够承接临床早期原料药CRO及制剂服务。2022年上半年,J-STAR实现营业收入1.31亿元,同比增长22%。返回搜狐,查看更多责任编辑:
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